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Olanzapine is an anti-manic or anti-psychotic agent, which helps in restoring the balance of natural chemicals in a patient s brain known as neurotransmitters.

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Olanzapine is effective in maintaining the clinical improvement during continuation therapy in patients who have shown an initial treatment response.

Dosage adjustmentsif necessaryshould be made at intervals greater than 24 hours.

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this finding was confirmed by a recent short-term 6-week clinical trial in which first episode schizophrenia patients with a combination treatment of olanzapine, betahistine and reboxetine a selective norepinephrine reuptake inhibitor had significantly less weight gain than those treated with olanzapine only 47 , while betahistine reboxetine combination treatment produced a two-fold larger weight-attenuating effect than reboxetine treatment alone 47 , 48 .


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