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Complicated skin and skin structure infectionsincluding diabetic foot infectionswithout concomitant osteomyelitiscaused by Staphylococcus aureusmethicillin-susceptible andresistant strainsStreptococcus pyogenesor Streptococcus agalactiaeZYVOX has not been studied in the treatment of decubitus ulcers.

Aged cheeses or meatspickled or fermented meatssmoked or air-dried meatssauerkrautsoy saucetap beeralcoholic and nonalcoholicred wineor any meatcheeseor other protein-based food that has been improperly stored.

To reduce the development of drug-resistant bacteria and maintain the effectiveness of ZYVOX and other antibacterial drugsZYVOX should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteriaWhen culture and susceptibility information are availablethey should be considered in selecting or modifying antibacterial therapyIn the absence of such datalocal epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

The prevalence of acquired resistance may vary geographically and with time for selected species and local information on resistance is desirableparticularly when treating severe infectionsAs necessaryexpert advice should be sought when local prevalence of resistance is such that the utility of the agent in at least some types of infections is questionable.

Store at room temperature away from light and moistureDo not store in the bathroomKeep all medications away from children and pets.

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